Methods of detecting T-cell activation
US6602660B1 · kind B1 · utility
3Cited by
2References
6Claims
0Family size
Inventors
Key dates
| Filing date | Aug 30, 2000 |
| Grant date | Aug 5, 2003 |
| Priority date | — |
| Expiry date | Aug 30, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/56972
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods of detecting activated T-cells involve monitoring levels of MUC-1 mucin expression at the protein and/or mRNA level. Compositions for modulating immune function contain compounds that modulate the expression or function of MUC-1. Methods of treating disorders associated an inappropriate state of T-cell activation involve contacting a T-cell with a compound containing an inhibitor of MUC-1 expression or function.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.