Process for the preparation of N-carboxyanhydrides
US6603016B2 · kind B2 · utility
3Cited by
1References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 30, 2002 |
| Grant date | Aug 5, 2003 |
| Priority date | — |
| Expiry date | May 30, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D263/44
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to an improved process for the preparation of N-carboxyanhydrides by reaction of the corresponding amino acid or one of its salts with phosgene, diphosgene and/or triphosgene in a solvent medium, characterized in that at least a portion of the reaction is carried out under a pressure of less than 1000 mbar. The N-carboxyanhydrides are thus obtained with better yields and an improved purity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.