Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
US6605294B2 · kind B2 · utility
523Cited by
34References
10Claims
0Family size
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Key dates
| Filing date | Aug 14, 1998 |
| Grant date | Aug 12, 2003 |
| Priority date | — |
| Expiry date | Aug 14, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/418
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pharmaceutically acceptable hydrogel polymers of natural, recombinant or synthetic origin, or hybrids thereof, are introduced in a dry, less hydrated, or substantially deswollen state and rehydrate in a physiological environment to undergo a volumetric expansion and to affect sealing, plugging, or augmentation of tissue, defects in tissue, or of organs. The hydrogel polymers may deliver therapeutic entities by controlled release at the site. Methods to form useful devices from such polymers, and to implant the devices are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.