Patent · US Expired

Antibiotic oxazolidinone derivatives

US6605630B1 · kind B1 · utility

13Cited by
30References
13Claims
0Family size

Assignee

Inventor

Key dates

Filing dateFeb 18, 2000
Grant dateAug 12, 2003
Priority date
Expiry dateFeb 18, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention concerns a compound of the formula (I): wherein, for example:T is of the formula (IA), (IB), or (IC); R1 is of the formula —NHC(═O)Rb wherein Rb is (1-4C)alkyl;R2 and R3 are hydrogen or fluoro;>A—B— is >C═CH— (but not when T is (IA)) or >CH—CH2—;wherein when T is of the formula (IA) or (IB);R6 is, for example, (1-4C)alkyl; R5 is hydrogen, R10CO—, R10SO2— or R10CS— wherein R10 is, for example, optionally substituted phenyl, or (1-10C)alkyl,or when T is of the formula (IA), (IB); or (IC):R5 and R6 are linked to give a 5- or 6-membered ring which is fused to the ring shown in (IA), (IB), or (IC) so as to give an optionally substituted bicyclic ring;and pharmaceutically acceptable salts thereof, processes for their preparation, pharmaceutical compositions containing them, and their use as antibacterial agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.