Methods for inhibiting and reducing amyloid fibril formation associated with Alzheimer's Disease and other amyloidoses
US6607758B2 · kind B2 · utility
11Cited by
6References
19Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 24, 2001 |
| Grant date | Aug 19, 2003 |
| Priority date | — |
| Expiry date | Aug 24, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of inhibiting amyloid formation, deposition, accumulation, or persistence, or amyloid protein-amyloid protein interactions, amyloid-proteoglycan interactions, amyloid-PG/GAG interactions and/or amyloid-glycosaminoglycan interactions, and/or dissolving or disrupting pre-formed or pre-deposited amyloid fibrils in Alzheimer's Disease in a mammalian subject. In the method a therapeutically effective amount of plant matter from the genus Uncaria, species tomentosa is administered, preferably from the inner bark or root tissue of Uncaria tomentosa.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.