Chemical modification of biomedical materials with genipin
US6608040B1 · kind B1 · utility
35Cited by
4References
17Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 27, 2001 |
| Grant date | Aug 19, 2003 |
| Priority date | — |
| Expiry date | Sep 27, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/40
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Biocompatible cross-linked materials, suitable for use in implants, wound dressings, and blood substitutes, are described. The materials are prepared by cross-linking biological substances, such as collagen, chitosan, or hemoglobin, with genipin, a naturally occurring cross-linking agent. The cross-linking agent has much lower toxicity than conventionally used reagents, and the cross-linked products have good thermal and mechanical stability as well as biocompatibility.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.