Use of PDT to inhibit intimal hyperplasia
US6609014B1 · kind B1 · utility
22Cited by
11References
22Claims
0Family size
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Key dates
| Filing date | Nov 17, 2000 |
| Grant date | Aug 19, 2003 |
| Priority date | — |
| Expiry date | Dec 3, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K41/0071
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Long-term dialysis requires provision of safe and reliable vascular access, often in the form of an arteriovenous (AV) fistula. The primary cause of AV fistula loss or failure is stenosis caused by intimal hyperplasia (IH) in the graft at the venous anastomosis or the distal vein. Disclosed are methods of using photodynamic therapy (PDT) to inhibit IH in blood vessels which may also be used to inhibit IH and SMC growth at the anastomosis of an AV fistula in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.