Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
US6610883B1 · kind B1 · utility
3Cited by
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17Claims
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Key dates
| Filing date | Jul 13, 1998 |
| Grant date | Aug 26, 2003 |
| Priority date | — |
| Expiry date | Jul 13, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, pyrrole, and polyenoic acid derivatives including carbocyclic polyenoic acids. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.