Method for producing 4-hydroxy-3-nitrobiphenyl

US6610893B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Horst Behre · Odenthal, DE
• Michael Dockner
• Alexander Klausener · Neunburg vorm Wald, DE

Key dates

• Filing date: Oct 7, 2002
• Grant date: Aug 26, 2003
• Expiry date: Oct 7, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C201/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process is provided for preparing 4-hydroxy-3-nitrobiphenyl from 4-hydroxy-biphenyl by nitrating in the position adjacent to the phenolic hydroxyl group in high selectivity and yield, and the nitric acid used as the nitrating reagent is metered into the reaction system in a specific manner.