Adaptation of virus to vertebrate cells
US6613556B1 · kind B1 · utility
2Cited by
0References
5Claims
0Family size
Assignee
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Key dates
| Filing date | Mar 24, 2000 |
| Grant date | Sep 2, 2003 |
| Priority date | — |
| Expiry date | Mar 24, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method for replicating virus to high titer in cultured mammalian cells by infecting the mammalian cells with the high titer virus strain to obtain infected cells, specifically, attenuated dengue virus strains of serotype 1, 2, 3, and 4. The resulting replicated virus is suitable for use in vaccines and vaccination methods which are also provided by the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.