COMBINATION OF PROSTACYCLIN WITH AN ESTROGEN OR PROGESTIN FOR THE PREVENTION AND TREATMENT OF ATHEROSCLEROTIC VASCULAR DISEASE INCLUDING PREECLAMPSIA AND FOR THE TREATMENT OF HYPERTENSION, AND FOR HORMONE REPLACEMENT THERAPY

US6613757B1 · kind B1 · utility

Assignee

• The Board of Regents of the University of Texas System · US

Inventors

• Robert E. Garfield · Goodyear, US
• Kristof Chwalisz · Berlin, DE

Key dates

• Filing date: Sep 22, 1994
• Grant date: Sep 2, 2003
• Expiry date: Sep 22, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P15/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Cardiovascular disease, including preeclampsia in pregnant women and hypertension in both women and men, are prevented or treated by administering thereto prostacyclin or a prostacyclin analog in combination with one or both of an estrogen and a progestin, which combination is also useful for HRT in peri- and post-menopausal women.