Method of treatment of viral infection including HIV using water soluble fullerenes

US6613771B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Simon H. Friedman · San Francisco, US
• Raymond F. Schinazi · Decatur, US
• Fred Wudl · Lompoc, US
• Craig L. Hill · Atlanta, US
• Diane L. DeCamp · Atlanta, US
• Rintje P. Sijbesma · 's-Hertogenbosch, NL
• George L. Kenyon · San Francisco, US

Key dates

• Filing date: Jan 25, 2001
• Grant date: Sep 2, 2003
• Expiry date: Jan 25, 2021

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S977/904
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A water soluble derivative of buckministerfullerene (C60) having antiviral and virucidal properties is used to inhibit human retroviral replication and infections. The derivatized fullerene is symmetrically substituted with polar organic moieties containing 1 to 20 carbon atoms and optionally further containing oxygen or nitrogen.