Imidazopyridine derivatives as phosphodiesterase VII inhibitors

US6613778B1 · kind B1 · utility

Assignee

• MERCK PATENT GESELLSCHAFT MIT BESHRANK TER HAFTUNG · DE

Inventors

• Hanse-Michael Eggenweiler · Weiterstadt, DE
• Karl-August Ackermann · Ober-Ramstadt, DE
• Rochust Jonas · Darmstadt, DE
• Michael Wolf · Darmstadt, DE
• Michael Gassen · Munich, DE
• Thomas Welge · Alsbach, DE

Key dates

• Filing date: May 3, 2002
• Grant date: Sep 2, 2003
• Expiry date: May 3, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula I in whichR1 denotes CONR4R5,R2 denotes H or A,R4 and R5, independently of one another, each denote H or A1,R3 denotes Hal,Hal denotes F, Cl, Br or I,A denotes alkyl having 1-4 carbon atoms,A1 denotes alkyl having 1-10 carbon atoms,X denotes alkylene having 1-4 carbon atoms, in which an ethylene group may also be replaced by a double or triple bond,and their physiologically acceptable salts and/or solvates, as phosphodiesterase VII inhibitors, and their use for the preparation of a medicament.