Modulators of protein tyrosine phosphatases (PTPases)
US6613903B2 · kind B2 · utility
2Cited by
1References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 9, 2001 |
| Grant date | Sep 2, 2003 |
| Priority date | — |
| Expiry date | Jul 9, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/4365
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel thienopyridines, novel compositions, methods of their use, and methods of their manufacture, where such compounds of Formula 1 are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) including PTP1B, T cell PTP, wherein X, R1, R2, R3, and R4 are defined more fully in the description. The compounds are useful in the treatment of type 1 diabetes, type 2 diabetes, impaired glucose tolerance, insulin resistance, obesity, and other diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.