Patent · US Expired

Enantiomerically enriched malonic acid monoesters substituted by a tertiary hydrocarbon radical, and their preparation

US6613934B1 · kind B1 · utility

57Cited by

1References

23Claims

0Family size

Assignee

Degussa AG · DE

Inventors

Udo Jegelka · Recklinghausen, DE
Wolfgang Kleemiss · Haltern, DE
Bruno Klotz-Berendes · Werne, DE
Marcel Feld · Cologne, DE

Key dates

Filing date	Jun 10, 1997
Grant date	Sep 2, 2003
Priority date	—
Expiry date	Jun 10, 2017

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P7/62
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to enantiomerically enriched malonic acid monoesters &agr;-monosubstituted by a tertiary hydrocarbon radical, or their salts, of the general formula I: in which R1, R3, R4 and R5 are identical or different hydrocarbon radicals, and wherein any two of the radicals R3, R4 and R5 may alternatively be present as a carbocyclic ring together with the quaternary carbon atom which they substitute, and M is hydrogen, one equivalent of a metal or an optionally substituted ammonium ion. The invention further relates to a process for the preparation of the enantiomerically enriched &agr;-monosubstituted malonic acid monoesters, or their salts, by enzymatic partial hydrolysis of the corresponding diesters.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.