Patent · US Expired

Human NK-3 related prostate specific gene-1

US6617129B2 · kind B2 · utility

2Cited by
0References
137Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 26, 1998
Grant dateSep 9, 2003
Priority date
Expiry dateJun 26, 2018

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2799/026
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a novel member of the NK family of homeobox genes. In particular, isolated nucleic acid molecules are provided encoding the human NK-3 prostate specific gene 1 (NKX3.1) protein. NKX3.1 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of NKX3.1 activity. Also provided are diagnostic methods for detecting prostate cancer and other cancers and therapeutic methods for prostate cancer and other cancers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.