Electroporation chamber including an electrode having a continuous, crystalline metal nitride coating
US6617154B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Nov 8, 2000 |
| Grant date | Sep 9, 2003 |
| Priority date | — |
| Expiry date | Nov 8, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/0424
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An improved electrode for use in generating an electrical field in a saline solution is provided. In particular, a continuous crystalline metal nitride coated electrode is provided for use in a variety of saline solution applications, such as in an electrophoresis device for separating proteins or nucleic acids or an electroporation apparatus for the encapsulation of biologically-active substances in various cell populations. A method and apparatus are provided for the encapsulation of biologically-active substances in red blood cells, characterized by an optionally automated, continuous-flow, self-contained electroporation system which allows withdrawal of blood from a patient, separation of red blood cells, encapsulation of a biologically-active substances in the cells, and optional recombination of blood plasma and the modified red blood cells thereby producing blood with modified biological characteristics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.