Anti-human VEGF receptor Flt-1 monoclonal antibody
US6617160B1 · kind B1 · utility
7Cited by
9References
10Claims
0Family size
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Key dates
| Filing date | Jul 20, 1998 |
| Grant date | Sep 9, 2003 |
| Priority date | — |
| Expiry date | Jul 20, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a monoclonal antibody which immunologically reacts with human VEGF receptor Flt-1 and cells in which human VEGF receptor Flt-1 is expressed on the cell surface and a monoclonal antibody which inhibits binding of human VEGF to human VEGF receptor Flt-1. It also provides a means for the diagnosis or treatment of diseases in which their morbid states progress by abnormal angiogensis, such as proliferation or metastasis of solid tumors, arthritis in rheumatoid, arthritis, diabetic retinopathy, retinopathy of prematurity, psoriasis, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.