Patent · US Expired

Method for producing n-butyryl-4-amino-3-methyl-methyl benzoate and the novel compound n-(4-bromine-2-methylphenyl)-butanamide

US6620962B2 · kind B2 · utility

0Cited by

0References

9Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Lars Rodefeld · Leverkusen, DE
Thomas Hopfner · Recklinghausen, DE
Alexander Klausener · Neunburg vorm Wald, DE
Horst Behre · Odenthal, DE

Key dates

Filing date	Sep 24, 2002
Grant date	Sep 16, 2003
Priority date	—
Expiry date	Sep 24, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C231/12
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

According to the invention, N-butyryl-4-amino-3-methyl-methyl benzoate is obtained in a particularly advantageous manner by, initially, reacting o-toluidine with butyric acid chloride, by brominating the reaction product and by reacting the bromide obtained therefrom with carbon monoxide and methanol in the presence of a palladium catalyst. The invention also relates to the important novel chemical compound N-(4-bromine-2-methylphenyl)-butanamide.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.