Methods and devices for reducing the mineral content of vascular calcified lesions
US6622732B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Mar 4, 2002 |
| Grant date | Sep 23, 2003 |
| Priority date | — |
| Expiry date | Mar 4, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2017/22098
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods and devices are provided for at least reducing the mineral content of a vascular calcified lesion, i.e. a calcified lesion present on the vascular tissue of a host. In the subject methods, the local environment of the lesion is maintained at a subphysiologic pH for a period of time sufficient for the mineral content of the lesion to be reduced, e.g. by flushing the lesion with a fluid capable of locally increasing the proton concentration in the region of the lesion. Also provided are systems and kits for practicing the subject methods. The subject methods and devices find particular use in the treatment of vascular diseases associated with the presence of calcified lesions on vascular tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.