Methods for producing 5′-nucleic acid-protein conjugates
US6623926B1 · kind B1 · utility
14Cited by
13References
26Claims
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Key dates
| Filing date | Jun 1, 2000 |
| Grant date | Sep 23, 2003 |
| Priority date | — |
| Expiry date | Oct 28, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein is a method for generating a 5′-nucleic acid-protein conjugate, the method involving: (a) providing a nucleic acid which carries a reactive group at its 5′ end; (b) providing a non-derivatized protein; and (c) contacting the nucleic acid and the protein under conditions which allow the reactive group to react with the N-terminus of the protein, thereby forming a 5′-nucleic acid-protein conjugate. Also disclosed herein are 5′-nucleic acid-protein conjugates and methods for their use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.