Calcium salts of lipopeptide antibiotics, method for producing same and their use

US6624143B1 · kind B1 · utility

Assignee

• Aventis Pharma Deutschland GmbH · DE

Inventors

• Laszlo Vertesy · Eppstein, DE
• Werner Aretz · Königstein, DE
• Heinrich Decker · Eppstein, DE
• Eberhard Ehlers · Hofheim, DE
• Michael Kurz · Neustadt, DE
• Frank Schmidt · Frankfurt, DE

Key dates

• Filing date: Aug 25, 2000
• Grant date: Sep 23, 2003
• Expiry date: Aug 25, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12R2001/045
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a calcium salt of the compound of formula (II), where R1 is a straight-chain or branched, saturated or unsaturated aliphatic acyl radical having 8 to 22 carbon atoms, which can optionally be interrupted by or linked to one or more phenyl or cycloalkyl groups and optionally interrupted by oxygen. The invention also relates to a method for producing said calcium salt and to its use as a medicine.