Hydroxyphenylvinylthiazoles

US6624182B1 · kind B1 · utility

Assignee

• Ciba Specialty Chemicals Corporation · US

Inventors

• Wolfgang Haap · Bad Kötzting, DE
• Werner Hölzl · Eschentzwiller, FR
• Dietmar Ochs · Schopfheim, DE
• Karin Puchtler · Fischingen, DE
• Marcel Schnyder · Wyhlen, DE

Key dates

• Filing date: Nov 16, 2000
• Grant date: Sep 23, 2003
• Expiry date: Feb 3, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D277/24
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The use of hydroxyphenylvinylthiazoles of formula whereinR1, R2, R3 and R4 are each independently of the others hydrogen; halogen; hydroxy, C1-C16-alkyl, C1-C16alkoxy, phenyl; phenyl-C1-C3alkyl; C6-C10aryloxy, amino, mono-C1-C5alkyl-amino, di-C1-C5alkylamino or -NO2; wherein at least one of the radicals R1, R2, R3 and R4 is hydroxy;R5 is C1-C5alkyl; C1-C5alkoxy; or unsubstituted or halo-, C1-C5alkyl-, C1-C5alkoxy-, hydroxy- or pyrrolidinyl-substituted phenyl; as microbicidal active ingredients is described. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds. Accordingly, they are suitable for the antimicrobial treatment, especially the preservation and disinfection, of surfaces.