Amide and diamide inhibitors of IMPDH enzyme for use in treating IMPDH-associated disorders
US6624184B1 · kind B1 · utility
31Cited by
34References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 27, 1999 |
| Grant date | Sep 23, 2003 |
| Priority date | — |
| Expiry date | Oct 27, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention discloses the identification of the inhibitors of IMPDH (inosine-5′-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH associated disorders, such as transplant rejection and autoimmune diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.