Diarylcycloalkyl derivatives, processes for their preparation and their use as pharmaceuticals

US6624185B2 · kind B2 · utility

Assignee

• Aventis Pharma Deutschland GmbH · DE

Inventors

• Heiner Glombik · Hofheim, DE
• Eugen Falk · Frankfurt am Main, DE
• Wendelin Frick · Bad Camberg, DE
• Stefanie Keil · Frankfurt am Main, DE
• Hans-Ludwig Schafer · Hochheim, DE
• Lothar Schwink · Stadtallendorf, DE
• Wolfgang Wendler · Bad Camberg, DE

Key dates

• Filing date: Aug 30, 2002
• Grant date: Sep 23, 2003
• Expiry date: Aug 30, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Diarylcycloalkyl derivatives and their physiologically acceptable salts and physiologically functional derivatives are disclosed. The compounds include those of formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparation. The compounds typically have lipid- and/or triglyceride-lowering properties and are suitable, for example, for the treatment of disorders of lipid metabolism, of type II diabetes, and of syndrome X.