Bioadhesive progressive hydration tablets
US6624200B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 11, 2001 |
| Grant date | Sep 23, 2003 |
| Priority date | — |
| Expiry date | Jul 15, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P5/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A bioadhesive composition wherein the active ingredient may be protected from water or the surrounding environment, thereby protecting it from metabolism or from other degradation caused by moisture, enzymes, or pH effects, and making it bioavailable only at a controlled rate. The active ingredient may be protected from moisture during the manufacturing process and more importantly may be protected from moisture and the immediate septic environment until after the patient has applied the composition, and then only at a slow and controlled rate. It is by this process of progressive hydration that the active ingredient remains protected for many hours after administration. It is also by the process of progressive hydration that controlled and sustained release is achieved because only that part of the active ingredient that is the hydrated (aqueous) fraction of the composition is available for absorption (bioavailable).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.