Epothilone minor constituents

US6624310B1 · kind B1 · utility

Assignee

• Gesellschaft fur Biotechnologische Forschung mbH (GBF) · DE

Inventors

• Gerhard Hoefle · Braunschweig, DE
• Hans Reichenbach · Braunschweig, DE
• Klaus Gerth · Braunschweig, DE
• Ingo Hardt · Braunschweig, DE
• Florenz Sasse · Braunschweig, DE
• Heinrich Steinmetz · Wennigsen (Deister), DE

Key dates

• Filing date: Mar 21, 2001
• Grant date: Sep 23, 2003
• Expiry date: Mar 21, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D493/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to compounds which are obtained by fermenting DSM 6773, especially epothilones A1, A2, A8, A9, B10, C1, C2, C3, C4, C5, C6, C7, C8, C9, D1, D2, D5, G1, G2, H1, H2, I1, I2, I3, I4, I5, I6 and K and trans-epothilones C1 and C2.