Patent · US Expired

Method of preventing abuse of opioid dosage forms

US6627635B2 · kind B2 · utility

244Cited by

69References

23Claims

0Family size

Assignee

Euro-Celtique S.A. · LU

Inventors

Philip J. Palermo · Bethel, US
Robert F. Kaiko · Weston, US
Robert D. Colucci · Newtown, US

Key dates

Filing date	Mar 22, 2001
Grant date	Sep 30, 2003
Priority date	—
Expiry date	Mar 22, 2021

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/36
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates in part to a method of reducing the abuse potential of an oral dosage form of an opioid analgesic, wherein an analgesically effective amount of an orally active opioid agonist is combined with an opioid antagonist into an oral dosage form which would require at least a two-step extraction process to be separated from the opioid agonist, the amount of opioid antagonist including being sufficient to counteract opioid effects if extracted together with the opioid agonist and administered parenterally.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.