Controlled release liquid delivery compositions with low initial drug burst
US6630155B1 · kind B1 · utility
171Cited by
6References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 22, 2000 |
| Grant date | Oct 7, 2003 |
| Priority date | — |
| Expiry date | Aug 22, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/0024
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a controlled release polymeric composition which includes a base polymer or copolymer, an organic solvent, a polymeric controlled release additive, and a biologically active agent. The polymeric controlled release additive reduces the initial burst of biologically active agent released from the polymeric composition as it is solidifying to form the solid implant. The controlled release additive is preferably a poly(lactide-co-glycolide)/polyethylene glycol block copolymer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.