Process for preparing major histocompatibility antigen class II protein and materials in which the same is bound
US6630315B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 11, 1997 |
| Grant date | Oct 7, 2003 |
| Priority date | — |
| Expiry date | Sep 11, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/70539
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention provides a process for producing major histocompatibility antigen class II protein (hereinafter referred to as “MHC class II” for short) which occurs on the surfaces of antigen-presenting cells and the like, and MHC class II-bound materials in which MHC class II, &agr; and/or &bgr; subunit of MHC class II, or a part thereof is bound to a carrier such as beads, fibers and hollow fibers via covalent bond, as well as a module for removing superantigen using the same. This invention also provides a method for detecting or quantifying superantigens using MHC class II or a part thereof having an affinity to the superantigens, as well as an assay kit therefor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.