Patent · US Expired

Quinoline derivatives as tyrosine kinase inhibitors

US6630489B1 · kind B1 · utility

36Cited by
0References
15Claims
0Family size

Assignee

Inventor

Key dates

Filing dateAug 20, 2001
Grant dateOct 7, 2003
Priority date—
Expiry dateAug 20, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention concerns quinoline derivatives of formula (I) wherein n is 0-3 and each R4, which may be the same or different, is a substituent such as halogeno, hydroxy, amino, nitro, trifluoromethyl, trifluoromethoxy, cyano or (1-6C)alkyl, or optionally substituted phenyl, phenoxy, anilino, N-(1-6C)alkylanilino, benzoyl or pyridyloxy; R1 and R2 is hydrogen or optionally substituted (1-6C)alkyl, (2-6C)alkenyl or (2-6C)alkynyl; or pharmaceutically-acceptable salts thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the prevention or treatment of T cell mediated diseases or medical conditions

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.