Substituted succinic acid metallo-&bgr;-lactamase inhibitors and their use in treating bacterial infections
US6630510B1 · kind B1 · utility
2Cited by
3References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 26, 2000 |
| Grant date | Oct 7, 2003 |
| Priority date | — |
| Expiry date | Oct 26, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to novel substituted succinic acid metallo-&bgr;-lactamase inhibitors which are useful potentiators of &bgr;-lactam antibiotics. Accordingly, the present invention provides a method of treating bacterial infections in animals or humans which comprises administering, together with a b-lactam antibiotic, a therapeutically effective amount of a compound of formula I: including pharmaceutically acceptable salts, prodrugs, anhydrides, and solvates thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.