Cryopreservation system with controlled dendritic freezing front velocity
US6631616B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Jul 15, 2002 |
| Grant date | Oct 14, 2003 |
| Priority date | — |
| Expiry date | Jul 15, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N1/42
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A biopharmaceutical cryopreservation system includes a container having an outer surface area with the container being adapted to contain a biopharmaceutical material for freezing and thawing therein. The container may be received in a cryocooling enclosure having an interior cavity configured to receive it. The cryocooling enclosure includes at least one heat transfer surface configured to contact the outer surface area of the container when the cryocooling enclosure interior cavity receives the container. Also, a cryocooler is thermally coupled to the cryocooling enclosure and is configured to flow a fluid to the at least one heat transfer surface to control the temperature of the heat transfer surface and the biopharmaceutical material within the container. The fluid is isolated from contacting the container. Further, a temperature sensor is thermally coupled to the cryocooling enclosure, the at least one heat transfer surface, the fluid and/or the cryocooler.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.