Composite hydrogel drug delivery systems
US6632457B1 · kind B1 · utility
243Cited by
66References
28Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 14, 1998 |
| Grant date | Oct 14, 2003 |
| Priority date | — |
| Expiry date | Aug 14, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K51/1213
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods are provided to control the release of relatively low molecular weight therapeutic species through hydrogels by first dispersing or dissolving such therapeutic species within relatively hydrophobic rate modifying agents to form a mixture. The mixture is formed into microparticles that are dispersed within bioabsorbable hydrogels, so as to release the water soluble therapeutic agents in a controlled fashion. Methods of using the compositions of the present invention in therapeutic systems are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.