Vaccine against Staphylococcus intoxication

US6632640B1 · kind B1 · utility

Assignee

• The United States of America as represented by the Secretary of the Army · US

Inventors

• John S. Lee · Hagerstown, US
• Peter Pushko · Frederick, US
• Jonathan F. Smith · Cary, US
• Robert G. Ulrich · Frederick, US

Key dates

• Filing date: Jul 9, 1999
• Grant date: Oct 14, 2003
• Expiry date: Jul 9, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2799/021
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Using nucleic acids encoding mutant SEA and SEB exotoxins from Staphylococcus aureus, compositions and methods for use in inducing an immune response which is protective against staphylococcal aureus intoxication in subjects is described.