Use of strains of parapoxvirus ovis against organ fibrosis

US6632647B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Claudia Hirth-Dietrich · Wuppertal, DE
• Tobias Schlapp · Goch, DE
• Angela Siegling · Brunn am Gebirge, AT
• Andreas Knorr · Erkrath, DE
• Olaf Weber · Wülfrath, DE
• Gudrun Theiss · Wuppertal, DE

Key dates

• Filing date: Jul 11, 2001
• Grant date: Oct 14, 2003
• Expiry date: Jul 11, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2710/24232
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to the use, in humans, of inactivated parapoxviruses for the prophylaxis and treatment of diseases which are accompanied by an increased deposition of collagen, with it being possible for both internal organs, such as the liver, and the skin and its appended structures, to be affected. The invention relates, in particular, to liver fibrosis and/or liver cirrhosis consequent upon virus hepatitis, or to ethanol-induced liver diseases and to cystic fibrosis.