Neuropilins and use thereof in methods for diagnosis and prognosis of cancer
US6635421B1 · kind B1 · utility
9Cited by
2References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 30, 2000 |
| Grant date | Oct 21, 2003 |
| Priority date | — |
| Expiry date | May 30, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to VEGF receptors (VEGFR) and neuropilins such as VEGF165R/NP-1 and NP-2 that are associated with metastatic potential of a malignant cell and their use in the diagnosis and prognosis of cancer. Preferred ones are VEGF165R/NP-1 and NP-2 but any neuropilin or VEGFR, where the constituents share at least about 85% homology with either of the above VEGF165R/NP-1 and NP-2 can be used. More preferably, such constituent shares at least 90% homology. Still more preferably, each constituent shares at least 95% homology.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.