LSR receptor, activity, cloning, and uses for diagnosing, preventing and/or treating obesity and related risks or complications
US6635431B1 · kind B1 · utility
Assignees
Inventors
Key dates
| Filing date | May 28, 1999 |
| Grant date | Oct 21, 2003 |
| Priority date | — |
| Expiry date | May 28, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a new complex receptor polypeptide LSR (Lipolysis Stimulated Receptor), characterized by its functional activities, the cloning of the cDNAs complementary to the messenger RNAs encoding each of the subunits of the multimeric complex, vectors and transformed cells, methods of diagnosis and of selection of compounds which can be used as medicament for the prevention and/or treatment of pathologies and/or of pathogeneses such as obesity and anorexia, hyperlipidemias, atherosclerosis, diabetes, hypertension, and more generally the various pathologies associated with abnormalities in the metabolism of cytokines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.