Lipoproteins as nucleic acid vectors
US6635623B1 · kind B1 · utility
52Cited by
33References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 14, 1998 |
| Grant date | Oct 21, 2003 |
| Priority date | — |
| Expiry date | May 14, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3513
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to materials and methods for the in vivo transport and deliver of nucleic acids. More particularly, it concerns the use of lipoproteins, including but not limited to, low density lipoproteins (“LDL”), and/or apolipoproteins for the binding and in vivo transport of nucleic acids. In addition, the present invention relates to the use of lipoproteins in the early detection of cancer and/or metastatic cancer and/or arteriosclerosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.