Adsorbent for reducing the concentration of fibrinogen and/or fibrin, method of producing an adsorber from the adsorbent, and an adsorber with the adsorbent
US6638710B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 9, 2001 |
| Grant date | Oct 28, 2003 |
| Priority date | — |
| Expiry date | May 24, 2021 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S210/905
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
An adsorbent for reducing the concentration of fibrinogen and/or fibrin in blood or blood plasma comprises a matrix and synthetic lateral chains that are covalently bonded to the matrix. The lateral synthetic chains are comprised of at least two amino groups in which the N2 atoms are at least 2.6 å apart within at least one lateral synthetic chain. The matrix exhibits porous, unaggregated, spherical particles in a range of particle sizes from 50 to 250 &mgr;m, which possess an exclusionary threshold of at least 107 Daltons, and they exhibit no peptides or aromatic groups of any kind. The at least two amino groups are preferably separated from one another by 4 to 6 carbon atoms. An adsorber for the purpose of reducing the concentration of fibrinogen and/or fibrin in blood or blood plasma may be produced from the adsorbent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.