Nucleotide sequences which code for the cma gene

US6638753B2 · kind B2 · utility

Assignees

• Degussa AG · DE
• Forschungszentrum Jülich GmbH · DE

Inventors

• Madhavan Nampoothiri K. · Thrissur, IN
• Bettina Mockel · Bielefeld, DE
• Lothar Eggeling · Jülich, DE
• Hermann Sahm · Jülich, DE

Key dates

• Filing date: May 1, 2001
• Grant date: Oct 28, 2003
• Expiry date: May 1, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P13/14
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to a genetically modified coryneform bacterium, the cma gene of which is amplified, and an isolated polynucleotide which codes for cyclopropane-mycolic acid synthase from coryneform bacteria, and also a method for the fermentative preparation of L-amino acids with amplification of the cma gene in the bacteria and the use of the polynucleotide as a primer or hydridization probe.