Compounds for protecting hydroxyls and methods for their use
US6639088B2 · kind B2 · utility
85Cited by
7References
26Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 12, 2001 |
| Grant date | Oct 28, 2003 |
| Priority date | — |
| Expiry date | Sep 12, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6816
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A hydrocarbyldithiomethyl-modified compound of the Formula:R1—O—CH2—S—S—R2 or a salt thereof wherein R1 is an organic molecule and R2 is a hydrocarbyl is useful for protecting and/or blocking hydroxyl groups in organic molecules such as nucleotides. The hydrocarbyldithiomethyl-modified compounds can also be used for chemically synthesizing oligonucleotides and for sequencing nucleic acid compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.