NMR spectroscopy data recovery method and apparatus
US6639405B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 4, 2002 |
| Grant date | Oct 28, 2003 |
| Priority date | — |
| Expiry date | Mar 13, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/4625
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
NMR spectroscopy data recovery methods and apparatus for improving the quality of an NMR spectrum are disclosed. The NMR spectrum is improved by acquiring more than the half spin-echo data signal and using an iterative numerical method to reconstruct the missing data points of the corresponding full symmetrical spin-echo data signal. The method includes filtering the initial data signal to extract a low-resolution phase term. The low-resolution phase term is used to form a phase-constrained initial data signal, which is Fourier-transformed to obtain a reconstructed data signal. The reconstructed data signal is modified to include the original spin-echo signal data. The formation of the reconstructed spin-echo data signal and subsequent modification is iterated until convergence is obtained. The reconstructed data signal is then Fourier-transformed to form a reconstructed NMR spectrum.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.