Method for inducing a response in one or more targeted cells
US6642018B1 · kind B1 · utility
86Cited by
31References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 13, 2000 |
| Grant date | Nov 4, 2003 |
| Priority date | — |
| Expiry date | Mar 13, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/56966
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method and apparatus is disclosed for selectively identifying, and targeting with an energy beam, specific cells within a mixed cell population, for the purpose of inducing a response in the targeted cells. Two or more fluorescent labels can be attached to the targeted cells, and distinguished from one another by a color camera. By use of this system, one can monitor and affect cells having a desired phenotype. For example, targeted cells can not only be inactivated by an energy beam, but can also be monitored through fluorescent labeling for changes in cell morphology, ion transport or other cellular functions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.