Crustacean antimicrobial peptides
US6642203B1 · kind B1 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 12, 2000 |
| Grant date | Nov 4, 2003 |
| Priority date | — |
| Expiry date | Apr 12, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns antimicrobial peptides obtained from penaeid prawns having the following characteristics: a molecular mass of about 5 to 7 kDa; a pHi not less than 9; an N-terminal portion comprising a region (A) of about 15 to 25 amino acids rich in proline; and a C-terminal portion comprising a region (B) of about 20 to 30 amino acids and containing 6 cysteine residues forming three intramolecular disulfide bonds. The invention also concerns the nucleic acid sequences coding for said peptides and enabling their production by genetic engineering.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.