Patent · US Expired

Crustacean antimicrobial peptides

US6642203B1 · kind B1 · utility

4Cited by
0References
9Claims
0Family size

Assignees

Inventors

Key dates

Filing dateApr 12, 2000
Grant dateNov 4, 2003
Priority date
Expiry dateApr 12, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention concerns antimicrobial peptides obtained from penaeid prawns having the following characteristics: a molecular mass of about 5 to 7 kDa; a pHi not less than 9; an N-terminal portion comprising a region (A) of about 15 to 25 amino acids rich in proline; and a C-terminal portion comprising a region (B) of about 20 to 30 amino acids and containing 6 cysteine residues forming three intramolecular disulfide bonds. The invention also concerns the nucleic acid sequences coding for said peptides and enabling their production by genetic engineering.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.