Patent · US Expired

Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors

US6642268B2 · kind B2 · utility

17Cited by
54References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 15, 2002
Grant dateNov 4, 2003
Priority date
Expiry dateFeb 15, 2022

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D495/10
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals. Also provided are compositions and methods for combination therapy employing ileal bile acid transport inhibitors and HMG Co—A reductase inhibitors for the treatment of hyperlipidemic conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.