Beaded polyethylene glycol-based resins
US6642334B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 9, 2001 |
| Grant date | Nov 4, 2003 |
| Priority date | — |
| Expiry date | Jan 21, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S526/936
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
Described herein is a pentaalkyldisiloxane containing polymeric surfactant prepared by the copolymerization of an alkoxypolyoxyalkylenyl acrylate and an acrylate containing a pentaalkyldisiloxane group. A method for preparing beaded polyethylene glycol-based resins in silicone oil in the presence of a polymeric surfactant containing a pentaalkyldisiloxane group is also described. The average bead size can be controlled by varying the stirring rate, the polymerization temperature, the amount of surfactant, the type of solvent, and the amount of solvent. The surfactant does not interfere with the polymerization and can be removed together with residual silicone oil by a simple washing procedure. The resins can be used, for example, as a support for solid phase organic synthesis, as a chromatographic resin, as a resin for solid phase MAS-NMR spectroscopy, and as a carrier for drug molecules, various reagents, or scavengers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.