Patent · US Expired

Loading metal particles into cell membrane vesicles and metal particular use for imaging and therapy

US6645464B1 · kind B1 · utility

36Cited by
13References
43Claims
0Family size

Inventor

Key dates

Filing dateJul 29, 1999
Grant dateNov 11, 2003
Priority date
Expiry dateJul 29, 2019

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S977/93
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Delivery of metal particles to living tissue, then applying external energy that interacts with the metal particles, is found to selectively increase the energy deposition and interaction surrounding the metal particles. The method is useful to improve treatment of various conditions, since targeted cells may be selectively altered or killed. Metal particles are also loaded into cells or membrane vesicles by placing metal seed particles into the cells or vesicles, then chemically depositing additional metal on the metal seed particles. The metal particles are useful to improve imaging and therapies by their interaction with externally applied energy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.