Antigen-specific IgG detection

US6645732B2 · kind B2 · utility

Assignee

• Roche Diagnostics GMBH · DE

Inventors

• Elke Faatz · Huglfing, DE
• Urban Schmitt · Oberhausen, DE

Key dates

• Filing date: Nov 8, 1999
• Grant date: Nov 11, 2003
• Expiry date: Nov 8, 2019

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/866
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention concerns a method for the determination of antigen-specific antibodies of the immunoglobulin G class in the presence of immunoglobulins of the M class in body fluids by incubation with at least two different receptors R1 and R2 and optionally additional receptors, an essential component of R2 being a binding partner in monomeric form, a reagent for determining an antigen-specific antibody of the immunoglobulin G class as well as the use of binding partners in monomeric form for the determination of an antigen-specific antibody of the immunoglobulin G class.