Method of treating diseased, injured or abnormal cartilage with hyaluronic acid and growth factors
US6645945B1 · kind B1 · utility
14Cited by
40References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 22, 1999 |
| Grant date | Nov 11, 2003 |
| Priority date | — |
| Expiry date | May 20, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition is provided for treating diseased, injured or diseased cartilage comprising hyaluronic acid and a growth factor. The composition has a viscosity and biodegradability sufficient to persist at the site for a period of time sufficient to alleviate the symptoms of the disease, injury or abnormality. Preferably hyaluronic acid is used in a composition range of 0.01-4% by weight and the preferred growth factor is IGF-I, present in a concentration range of about 10−6 to 100 mg/ml.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.